Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009963 | 0.90 | FFAR4 (0.54) | FFAR4EPHX2FFAR1PTGS2POLB | |
| SCHEMBL27643599 | 0.88 | FFAR4 (0.43) | FFAR4EPHX2PTGS2POLBGAA | |
| SCHEMBL9644005 | 0.85 | NPSR1 (0.44) | FFAR4EPHX2FFAR1POLBPTGER1 | |
| SCHEMBL1567998 | 0.85 | FFAR4 (0.48) | FFAR4EPHX2FFAR1POLB | |
| SCHEMBL1953231 | 0.84 | EPHX2 (0.59) | FFAR4EPHX2FFAR1POLBGAA | |
| SCHEMBL29733422 | 0.84 | EPHX2 (0.59) | FFAR4EPHX2FFAR1POLBGAA | |
| Trifluoroacetic Acid SCHEMBL30151156 | 0.83 | EPHX2 (0.41) | FFAR4EPHX2FFAR1PTGS2POLB | |
| SCHEMBL29525642 | 0.83 | PTGS2 (0.57) | FFAR4EPHX2PTGS2P2RX7 | |
| SCHEMBL305056 | 0.83 | PTGS2 (0.57) | FFAR4EPHX2PTGS2P2RX7 | |
| SCHEMBL11523361 | 0.82 | EPHX2 (0.48) | FFAR4EPHX2FFAR1PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | claimed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | claimed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | claimed |
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | disclosed |