Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 10/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152013 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL5166825 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL2395752 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL925036 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL18339201 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL8579272 | 0.98 | ALDH1A1 (0.59) | ALDH1A1ELANEEGFRERBB2DGKA | |
| Alcohol SCHEMBL8207628 | 0.97 | ALDH1A1 (0.55) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL155116 | 0.94 | ALDH1A1 (0.61) | ALDH1A1ELANEEGFRERBB2 | |
| SCHEMBL11002116 | 0.92 | ALDH1A1 (0.62) | ALDH1A1ELANEEGFRERBB2 | |
| SCHEMBL11001635 | 0.92 | ALDH1A1 (0.62) | ALDH1A1ELANEEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121437-A1 | PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-01-25 | — | — | EP | disclosed |