Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 11/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166825 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL925036 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL2395752 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL30152028 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL18339201 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL30152013 | 0.97 | ALDH1A1 (0.58) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL8579272 | 0.96 | ALDH1A1 (0.59) | ALDH1A1ELANEEGFRERBB2DGKA | |
| SCHEMBL155116 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ELANEEGFRERBB2POLB | |
| SCHEMBL11002116 | 0.90 | ALDH1A1 (0.62) | ALDH1A1ELANEEGFRERBB2POLB | |
| SCHEMBL11001635 | 0.90 | ALDH1A1 (0.62) | ALDH1A1ELANEEGFRERBB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6068939-A | ULTRA-FINE PARTICLES OF AT LEAST ONE PRECIOUS METAL, A FIXING AGENT COMPRISING AN ORGANIC METAL COMPOUND, A BINDER RESIN, A GLASS NETWORK FORMING COMPONENT FORMED OF AN ORGANIC COMPOUND CONTAINING SI, B OR P, AND AN ORGANIC SOLVENT. | MITSUBOSHI BELTING LTD. (JP) | 2000-05-30 | — | — | US | disclosed |