SCHEMBL30152091

SCHEMBL30152091

Brc1ccc2sc3ccccc3c2c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
MAPT P10636 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
DUSP3 P51452 2/20 0.42
MEN1 O00255 2/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 2/20 0.42
BLM P54132 1/20 0.42
PTPN5 P54829 1/20 0.42
PTPN11 Q06124 1/20 0.42
MCL1 Q07820 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
PTPN1 P18031 3/20 0.42
RAB9A P51151 3/20 0.38
HPGD P15428 2/20 0.38
NPC1 O15118 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2563740 1.00 GPR3 (0.50) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL23765077 0.81 GPR3 (0.46) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL22303409 0.81 GPR3 (0.46) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL17985428 0.81 GPR3 (0.46) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL1636538 0.80 GPR3 (0.68) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL29520053 0.79 GPR3 (0.54) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL29869583 0.79 GPR3 (0.54) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL7912643 0.79 GPR3 (0.54) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL22688468 0.77 GPR3 (0.46) GPR3MAPTTDP1DUSP3MEN1
SCHEMBL16985163 0.76 GPR3 (0.62) GPR3MAPTTDP1DUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240065097-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2024-02-22 US disclosed
US-11626561-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2023-04-11 US disclosed
EP-3820965-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11626561-B2 Materials for organic light emitting devices DDT, ESD, ETFA GPR3 2701/4885MAPT 612/4885TDP1 3006/4885
US-20240065097-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA GPR3 2701/4885MAPT 612/4885TDP1 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.