Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 16/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803908 | 1.00 | GPR52 (0.42) | GPR52THRBNPC1MAPTRAB9A | |
| SCHEMBL30120818 | 1.00 | GPR52 (0.42) | GPR52THRBNPC1MAPTRAB9A | |
| SCHEMBL30121029 | 0.89 | GPR52 (0.44) | GPR52 | |
| SCHEMBL23824115 | 0.89 | GPR52 (0.44) | GPR52 | |
| SCHEMBL23803831 | 0.88 | GPR52 (0.52) | GPR52 | |
| SCHEMBL30120785 | 0.88 | GPR52 (0.52) | GPR52 | |
| SCHEMBL23803891 | 0.84 | GPR52 (0.54) | GPR52THRBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30120873 | 0.84 | GPR52 (0.54) | GPR52THRBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31096950 | 0.81 | GPR52 (0.41) | GPR52MAPTALDH1A1 | |
| SCHEMBL23803883 | 0.76 | GPR52 (0.55) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515681-A | GPR52 modulator compounds | 赫普泰雅治疗有限公司 | 2022-12-23 | — | — | CN | disclosed |