Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824115 | 1.00 | GPR52 (0.44) | GPR52ALKBH1RORCCMA1 | |
| SCHEMBL23803831 | 0.91 | GPR52 (0.52) | GPR52 | |
| SCHEMBL30120785 | 0.91 | GPR52 (0.52) | GPR52 | |
| SCHEMBL30120818 | 0.89 | GPR52 (0.42) | GPR52 | |
| SCHEMBL23803908 | 0.89 | GPR52 (0.42) | GPR52 | |
| SCHEMBL30152262 | 0.89 | GPR52 (0.42) | GPR52 | |
| SCHEMBL23803849 | 0.83 | GPR52 (0.57) | GPR52RORCCMA1 | |
| SCHEMBL30120969 | 0.83 | GPR52 (0.57) | GPR52RORCCMA1 | |
| SCHEMBL23803837 | 0.74 | GPR52 (0.56) | GPR52 | |
| SCHEMBL30152179 | 0.74 | GPR52 (0.56) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4117784-B1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2024-08-28 | — | — | EP | disclosed |
| US-20240254101-A1 | GPR52 MODULATOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-08-01 | — | — | US | disclosed |
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254101-A1 | GPR52 MODULATOR COMPOUNDS | GPR52, GPR119, GPR4 | GPR52 1/4885ALKBH1 4623/4885RORC 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.