Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.65 |
| ▸ | FBP1 | P09467 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365440 | 0.83 | CYP19A1 (0.73) | NFE2L2FBP1CYP19A1MAPTRAB9A | |
| SCHEMBL3365445 | 0.83 | CYP19A1 (0.73) | NFE2L2FBP1CYP19A1MAPTRAB9A | |
| SCHEMBL20995875 | 0.80 | NFE2L2 (1.00) | NFE2L2 | |
| SCHEMBL20995879 | 0.80 | NFE2L2 (1.00) | NFE2L2 | |
| SCHEMBL12972517 | 0.78 | CYP19A1 (0.49) | NFE2L2FBP1CYP19A1MAPTRAB9A | |
| SCHEMBL13092117 | 0.75 | ALDH1A1 (0.49) | CYP19A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11776992 | 0.75 | CYP19A1 (0.69) | NFE2L2FBP1CYP19A1MAPTRAB9A | |
| SCHEMBL11776986 | 0.75 | CYP19A1 (0.69) | NFE2L2FBP1CYP19A1MAPTRAB9A | |
| SCHEMBL24969525 | 0.74 | NFE2L2 (0.75) | NFE2L2CYP19A1 | |
| SCHEMBL15498134 | 0.74 | NFE2L2 (0.89) | NFE2L2FBP1CYP19A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |