Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 5/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943180 | 0.78 | KMT2A (0.53) | BRD4ALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL17434178 | 0.78 | KMT2A (0.53) | BRD4ALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL30152376 | 0.77 | MEN1 (0.42) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL3590372 | 0.73 | PARP1 (0.54) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL2100537 | 0.73 | PARP1 (0.54) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL2101407 | 0.73 | PARP1 (0.54) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL190001 | 0.73 | KMT2A (0.46) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL11040723 | 0.72 | CA2 (0.64) | BRD4PGRNR3C1ARKDM4E | |
| SCHEMBL4968968 | 0.70 | BRD4 (0.48) | BRD4ALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL6997454 | 0.70 | KMT2A (0.55) | ALDH1A1CYP1A2CYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230115350-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115350-A1 | TEAD INHIBITORS AND USES THEREOF | TEAD2, TEAD3, TEAD4 | BRD4 988/4885ALDH1A1 1319/4885CYP1A2 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.