Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818732 | 1.00 | VSIR (0.37) | VSIRS1PR1S1PR3CETPKISS1R | |
| SCHEMBL24819018 | 0.91 | VSIR (0.40) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24820046 | 0.88 | VSIR (0.39) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24820345 | 0.87 | S1PR1 (0.41) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24820344 | 0.86 | VSIR (0.42) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24820048 | 0.85 | VSIR (0.39) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24818674 | 0.85 | VSIR (0.40) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24819904 | 0.85 | VSIR (0.52) | VSIR | |
| SCHEMBL24818905 | 0.85 | VSIR (0.36) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24819924 | 0.85 | VSIR (0.37) | VSIRS1PR1S1PR3CETPCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |