Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820344 | 0.94 | VSIR (0.42) | VSIRCETPS1PR1S1PR3MTNR1A | |
| SCHEMBL24818732 | 0.91 | VSIR (0.37) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL30152807 | 0.91 | VSIR (0.37) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL24820345 | 0.90 | S1PR1 (0.41) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL30153193 | 0.89 | VSIR (0.42) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL24818922 | 0.89 | VSIR (0.42) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL24820048 | 0.89 | VSIR (0.39) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL24818674 | 0.89 | VSIR (0.40) | VSIRCETPHPGDS1PR1S1PR3 | |
| SCHEMBL24819904 | 0.88 | VSIR (0.52) | VSIR | |
| SCHEMBL24818905 | 0.88 | VSIR (0.36) | VSIRCETPHPGDS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |