Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161841 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TDP1CTSBPMM2MPI | |
| SCHEMBL3390153 | 0.84 | TDP1 (0.52) | ALDH1A1TDP1MEN1KMT2AUSP2 | |
| SCHEMBL9452627 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TDP1CTSBPMM2MPI | |
| SCHEMBL11551067 | 0.84 | TDP1 (0.52) | ALDH1A1TDP1MEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL5914596 | 0.82 | TDP1 (0.50) | ALDH1A1TDP1MEN1KMT2AUSP2 | |
| SCHEMBL399100 | 0.79 | TDP1 (0.43) | ALDH1A1TDP1MEN1KMT2AUSP2 | |
| SCHEMBL1249766 | 0.77 | TSHR (0.59) | ALDH1A1TDP1CTSBPMM2MPI | |
| SCHEMBL1056952 | 0.77 | TDP1 (0.45) | ALDH1A1TDP1CTSBPMM2MPI | |
| SCHEMBL17934 | 0.77 | TSHR (0.59) | ALDH1A1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL16397274 | 0.75 | PMM2 (0.47) | ALDH1A1TDP1PMM2MPIMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |