Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | CBLB | Q13191 | 3/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820329 | 1.00 | VSIR (0.34) | VSIRCETPHTR3ACDK9CBLB | |
| SCHEMBL24818797 | 0.99 | VSIR (0.34) | VSIRCETPHTR3ACDK9CBLB | |
| SCHEMBL30152636 | 0.99 | VSIR (0.34) | VSIRCETPHTR3ACDK9CBLB | |
| SCHEMBL30152666 | 0.89 | VSIR (0.34) | VSIRCETPCBLBHPGDS1PR1 | |
| SCHEMBL24820425 | 0.89 | VSIR (0.34) | VSIRCETPCBLBHPGDS1PR1 | |
| SCHEMBL24818772 | 0.88 | VSIR (0.40) | VSIRCBLBS1PR1S1PR3 | |
| SCHEMBL30152788 | 0.86 | VSIR (0.40) | VSIRCETPHTR3ACBLBS1PR1 | |
| SCHEMBL24818925 | 0.86 | VSIR (0.40) | VSIRCETPHTR3ACBLBS1PR1 | |
| SCHEMBL24818822 | 0.86 | VSIR (0.34) | VSIRCETPCBLBHPGD | |
| SCHEMBL30152901 | 0.86 | VSIR (0.34) | VSIRCETPCBLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |