Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152666 | 1.00 | VSIR (0.34) | VSIRCHRNA7KCNH2S1PR1S1PR3 | |
| SCHEMBL24818822 | 0.91 | VSIR (0.34) | VSIRCETPCBLBHPGD | |
| SCHEMBL30152901 | 0.91 | VSIR (0.34) | VSIRCETPCBLBHPGD | |
| SCHEMBL30152896 | 0.89 | VSIR (0.34) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24820329 | 0.89 | VSIR (0.34) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL30152636 | 0.89 | VSIR (0.34) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24818797 | 0.89 | VSIR (0.34) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL24818674 | 0.83 | VSIR (0.40) | VSIRS1PR1S1PR3CETPCBLB | |
| SCHEMBL29189950 | 0.83 | CHRNA7 (0.39) | CHRNA7KCNH2S1PR1S1PR3USP2 | |
| SCHEMBL24821954 | 0.82 | CBLB (0.33) | VSIRKCNH2S1PR1CETPCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |