SCHEMBL30152932

SCHEMBL30152932

Cn1cnnc1-c1cc(F)ccc1-c1cc(-c2nc3cc(CN4CCC5(CC5)C4)cc(C(F)(F)F)c3[nH]2)nc(C2CC2)c1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 8/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24818903 1.00 CBLB (0.39) CBLB
SCHEMBL24819962 0.93 CBLB (0.38) CBLB
SCHEMBL30152648 0.93 CBLB (0.38) CBLB
SCHEMBL29190091 0.88 CBLB (0.38) CBLB
SCHEMBL24820601 0.88 CBLB (0.38) CBLB
SCHEMBL30152734 0.88 CBLB (0.38) CBLB
SCHEMBL24820706 0.87 CBLB (0.39) CBLB
SCHEMBL30152762 0.87 CBLB (0.39) CBLB
SCHEMBL24818860 0.84 CBLB (0.36) CBLB
SCHEMBL30153085 0.84 CBLB (0.36) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4359381-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-05-01 — — EP disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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