Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 12/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818784 | 1.00 | VSIR (0.41) | VSIRPDCD1CD274UTRNNPC1 | |
| SCHEMBL24819847 | 0.93 | KDM4E (0.41) | VSIRPDCD1CD274UTRNNPC1 | |
| SCHEMBL30152980 | 0.87 | VSIR (0.38) | VSIRPDCD1CD274UTRNNPC1 | |
| SCHEMBL24820770 | 0.87 | VSIR (0.38) | VSIRPDCD1CD274UTRNNPC1 | |
| SCHEMBL24819912 | 0.86 | TP53 (0.43) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL30153065 | 0.85 | VSIR (0.42) | VSIRPDCD1CD274NPC1RAB9A | |
| SCHEMBL24820049 | 0.85 | VSIR (0.42) | VSIRPDCD1CD274NPC1RAB9A | |
| SCHEMBL24821901 | 0.85 | VSIR (0.42) | VSIRPDCD1CD274NPC1RAB9A | |
| SCHEMBL24818786 | 0.84 | UTRN (0.38) | VSIRPDCD1CD274UTRNNPC1 | |
| SCHEMBL30153038 | 0.84 | UTRN (0.38) | VSIRPDCD1CD274UTRNNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |