Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 10/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153065 | 1.00 | VSIR (0.42) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL24820049 | 0.93 | VSIR (0.42) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL24820720 | 0.91 | VSIR (0.41) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL24819923 | 0.91 | VSIR (0.42) | VSIRHPGDPDCD1CD274ESR1 | |
| SCHEMBL30153044 | 0.91 | VSIR (0.41) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL30152561 | 0.91 | VSIR (0.42) | VSIRHPGDPDCD1CD274ESR1 | |
| SCHEMBL24818674 | 0.90 | VSIR (0.40) | VSIRHPGD | |
| SCHEMBL24820062 | 0.90 | VSIR (0.40) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL24821896 | 0.90 | VSIR (0.40) | VSIRHPGDLMNAGAAPDCD1 | |
| SCHEMBL24818878 | 0.90 | VSIR (0.40) | VSIRHPGDPDCD1CD274MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |