SCHEMBL30153104

SCHEMBL30153104

Cn1cnnc1-c1cc(F)ccc1-c1cc(-c2nc3cc(CO)cc(F)c3o2)cc(C2CC2)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ VSIR Q9H7M9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24821966 1.00 VSIR (0.31) VSIR
SCHEMBL24818791 0.89 CBLB (0.34) VSIR
SCHEMBL30153230 0.89 CBLB (0.34) VSIR
SCHEMBL30152929 0.88 CBLB (0.33) VSIR
SCHEMBL24820581 0.88 CBLB (0.33) VSIR
SCHEMBL24819948 0.88 S1PR1 (0.35) —
SCHEMBL30152971 0.88 S1PR1 (0.35) —
SCHEMBL24818782 0.88 CBLB (0.33) VSIR
SCHEMBL30152778 0.88 CBLB (0.33) VSIR
SCHEMBL24821901 0.87 VSIR (0.42) VSIR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4359381-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-05-01 — — EP disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
Send feedback