Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 12/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153213 | 0.88 | CBLB (0.37) | CBLBLMNAGAAEEF2KPLK1 | |
| SCHEMBL30152651 | 0.80 | CBLB (0.40) | CBLB | |
| SCHEMBL30153218 | 0.79 | CETP (0.32) | CBLB | |
| SCHEMBL30152722 | 0.78 | MAPK13 (0.35) | CBLBMAP3K5LMNAGAA | |
| SCHEMBL24819935 | 0.74 | CBLB (0.47) | CBLB | |
| SCHEMBL30153117 | 0.74 | CBLB (0.47) | CBLB | |
| SCHEMBL29920504 | 0.74 | MAPK13 (0.37) | CBLBLMNAGAA | |
| SCHEMBL27086018 | 0.74 | MAPK13 (0.37) | CBLBLMNAGAA | |
| SCHEMBL30153246 | 0.73 | CBLB (0.37) | CBLB | |
| SCHEMBL29190056 | 0.73 | CBLB (0.37) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |