Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.50 |
| ▸ | CBL | P22681 | 18/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819919 | 1.00 | CBLB (0.50) | CBLBCBL | |
| SCHEMBL24818908 | 0.88 | CBLB (0.39) | CBLBCBL | |
| SCHEMBL30792016 | 0.87 | CBLB (0.50) | CBLBCBL | |
| SCHEMBL30152674 | 0.87 | CBLB (0.50) | CBLBCBL | |
| SCHEMBL30153109 | 0.86 | CBLB (0.53) | CBLBCBL | |
| SCHEMBL24821953 | 0.81 | ESR1 (0.35) | CBLBCBL | |
| SCHEMBL30153030 | 0.77 | CBLB (0.47) | CBLBCBL | |
| SCHEMBL24819910 | 0.77 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL30792112 | 0.77 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL30152954 | 0.77 | CBLB (0.51) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |