Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290361 | 0.82 | SMN1; SMN2 (0.54) | HPGDNPSR1SMN1; SMN2TP53NPC1 | |
| SCHEMBL6161213 | 0.81 | ALDH1A1 (0.62) | HPGDNPSR1SMN1; SMN2NPC1TSHR | |
| SCHEMBL5792711 | 0.80 | KDM4E (0.50) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL31418181 | 0.79 | CPT2 (0.45) | CHRNB2HPGDNPSR1SMN1; SMN2TP53 | |
| SCHEMBL3669791 | 0.78 | ALDH1A1 (0.58) | HPGDNPSR1SMN1; SMN2NPC1TSHR | |
| SCHEMBL5697246 | 0.77 | ALDH1A1 (0.68) | HPGDNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5909093 | 0.76 | HPGD (0.52) | HPGDNPSR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL830508 | 0.74 | KMT2A (0.45) | HPGDNPSR1SMN1; SMN2TP53NPC1 | |
| SCHEMBL10529454 | 0.71 | MKNK1 (0.51) | CHRNB2MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL830088 | 0.69 | KMT2A (0.52) | HPGDSMN1; SMN2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230063805-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230063805-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | HCRTR2, HCRTR1, CNR2 | CHRNB1 399/4885CHRNB2 191/4885CHRNB4 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.