Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 6/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807130 | 0.83 | MAPT (0.43) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL21055714 | 0.83 | MAPT (0.43) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL29209088 | 0.79 | TSHR (0.43) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28198217 | 0.78 | MAPT (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL6971720 | 0.78 | — | — | |
| SCHEMBL1023939 | 0.78 | MAPT (0.60) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL7312659 | 0.78 | MAPT (0.50) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL29564 | 0.77 | — | — | |
| SCHEMBL6971723 | 0.77 | — | — | |
| SCHEMBL7448963 | 0.76 | MAPT (0.45) | MAPTCACNA1BAPBA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076425-B2 | Carbamate functional silica compounds and methods of making and use thereof | BASF COATINGS GMBH (DE) | 2011-12-13 | — | — | US | disclosed |
| EP-1794168-B1 | CARBAMATE FUNCTIONAL SILICA COMPOUNDS AND METHOD OF MAKING AND USE THEREOF | BASF CORP (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20070232776-A1 | Carbamate functional silica compounds and methods of making and use thereof | BASF CORPORATION (US) | 2007-10-04 | — | — | US | disclosed |
| EP-1794168-A1 | CARBAMATE FUNCTIONAL SILICA COMPOUNDS AND METHOD OF MAKING AND USE THEREOF | Basf Corporation (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006039447-A1 | CARBAMATE FUNCTIONAL SILICA COMPOUNDS AND METHOD OF MAKING AND USE THEREOF | BASF CORPORATION (US) | 2006-04-13 | — | — | WO | disclosed |