Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729016 | 0.88 | MAPT (0.50) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL7312659 | 0.85 | MAPT (0.50) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL27372531 | 0.82 | MAPT (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL1076421 | 0.82 | MAPT (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL2357850 | 0.80 | MAPT (0.44) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL9425493 | 0.80 | MAPT (0.48) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL11336077 | 0.79 | MAPT (0.49) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL7448963 | 0.79 | MAPT (0.45) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL22811355 | 0.79 | MAPT (0.45) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL1586225 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173742-B2 | Synthesis of biurets and isocyanates with alkoxysilane functions, formulations containing same and use thereof | PERSTORP FRANCE (FR) | 2012-05-08 | — | — | US | disclosed |
| US-20110065957-A1 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | PERSTORP FRANCE (FR) | 2011-03-17 | — | — | US | disclosed |
| US-7875693-B2 | reacting hexamethylene diisocyanate with aminopropy/ltrimethoxysilane/3-/ to form intermediate isocyanatoalkylsilane and reacting the isocyanatoalkylsilane with an isocyanate to form a biuret | PERSTORP FRANCE (FR) | 2011-01-25 | — | — | US | disclosed |
| US-20070015895-A1 | Synthesis of biurets and isocyanates with alkoxysilane functions, formulations containing same and use thereof | RHODIA OPERATIONS (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1117716-B1 | OLIGOMERIC AND HIGH-MOLECULAR CONVERSION PRODUCTS OF ALLOPHANIC ACID ESTERS WITH NUCLEOPHILIC COMPOUNDS , AND THE USE THEREOF | BASF COATINGS AG (DE) | 2004-11-17 | — | — | EP | disclosed |
| EP-0718290-B1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| EP-1117716-A1 | OLIGOMERIC AND HIGH-MOLECULAR CONVERSION PRODUCTS OF ALLOPHANIC ACID ESTERS WITH NUCLEOPHILIC COMPOUNDS AND LOW-MOLECULAR, OLIGOMERIC AND HIGH-MOLECULAR COMPOUNDS WITH ALLOPHANATE SIDE AND/OR TERMINAL GROUPS, AND THE USE THEREOF | BASF Coatings AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000012578-A1 | OLIGOMERIC AND HIGH-MOLECULAR CONVERSION PRODUCTS OF ALLOPHANIC ACID ESTERS WITH NUCLEOPHILIC COMPOUNDS AND LOW-MOLECULAR, OLIGOMERIC AND HIGH-MOLECULAR COMPOUNDS WITH ALLOPHANATE SIDE AND/OR TERMINAL GROUPS, AND THE USE THEREOF | BASF COATINGS AG (DE) | 2000-03-09 | — | — | WO | disclosed |
| US-5912261-A | ANTIDIABETIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0718290-A1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-4520147-A | TRIAZOLIDINE-3,5-DIONES; SELF-EXTINQUISHING | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| US-4396736-A | TRIAZOLIDINE-3,5-DIONES OR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-02 | — | — | US | disclosed |
| EP-0003870-A1 | Aqueous polymer resin emulsions and water-based paints and coatings containing such emulsions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1979-09-05 | — | — | EP | disclosed |
| US-3933846-A | FUNGICIDES, OVICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065957-A1 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | THEM6, INMT, BCAT2 | MAPT 363/4885CACNA1B 3708/4885APBA1 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.