Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312659 | 0.82 | MAPT (0.50) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL1023939 | 0.79 | MAPT (0.60) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL729016 | 0.77 | MAPT (0.50) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL3015689 | 0.76 | MAPT (0.47) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL2357850 | 0.74 | MAPT (0.44) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL11336079 | 0.73 | MAPT (0.41) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL18621628 | 0.71 | MAPT (0.40) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL27372531 | 0.71 | MAPT (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL6971720 | 0.71 | — | — | |
| SCHEMBL1076421 | 0.71 | MAPT (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971916-A1 | N-(ARGINYL)BENZENESULPHONAMIDE DERIVATIVES AND USE THEREOF AS ANTITHROMBOTIC AGENTS | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042700-A1 | N-(ARGINYL)BENZENESULPHONAMIDE DERIVATIVES AND USE THEREOF AS ANTITHROMBOTIC AGENTS | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |