Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658663 | 0.95 | OPRM1 (0.78) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30157177 | 0.94 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30833622 | 0.92 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29702054 | 0.92 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL31412199 | 0.92 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| Endomorphin 2 SCHEMBL29387366 | 0.92 | OPRM1 (0.76) | OPRM1OPRD1OPRK1 | |
| Endomorphin 2 SCHEMBL13252092 | 0.92 | OPRM1 (0.76) | OPRM1OPRD1OPRK1 | |
| Endomorphin 2 SCHEMBL22649436 | 0.92 | OPRM1 (0.76) | OPRM1OPRD1OPRK1 | |
| Endomorphin 2 SCHEMBL29577635 | 0.92 | OPRM1 (0.76) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3635117 | 0.90 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11590197-B2 | Agents targeting inhibitor of apoptosis proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11590197-B2 | Agents targeting inhibitor of apoptosis proteins | XIAP, BIRC2, BIRC5 | OPRM1 4783/4885OPRD1 4685/4885OPRK1 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.