Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157298 | 0.87 | P2RX7 (0.53) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL30157737 | 0.86 | EPHX2 (0.56) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30157904 | 0.82 | P2RX7 (0.44) | ALDH1A1TSHRHTTMAPTGAA | |
| SCHEMBL31706123 | 0.81 | HTT (0.54) | ALDH1A1TSHRHTTMAPTGAA | |
| SCHEMBL30157493 | 0.81 | P2RX7 (0.54) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL31706616 | 0.80 | CYP2D6 (0.58) | ALDH1A1TSHRHTTMAPTGAA | |
| SCHEMBL21176228 | 0.77 | HTT (0.61) | ALDH1A1TSHRALOX15TP53HTT | |
| SCHEMBL30157397 | 0.77 | CYP2D6 (0.51) | ALDH1A1TSHRHTTMAPTGAA | |
| SCHEMBL31706553 | 0.77 | CYP2D6 (0.48) | ALDH1A1HTTMAPTGAAMEN1 | |
| SCHEMBL30157290 | 0.77 | P2RX7 (0.53) | KMT2AP2RX7HPGDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |