Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157493 | 0.89 | P2RX7 (0.54) | P2RX7CYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL30157807 | 0.84 | TSHR (0.47) | P2RX7TSHRGAAMEN1KMT2A | |
| SCHEMBL30157811 | 0.84 | P2RX7 (0.42) | P2RX7CYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL30157681 | 0.83 | P2RX7 (0.53) | P2RX7KMT2ACAPN1 | |
| SCHEMBL30157565 | 0.83 | P2RX7 (0.53) | P2RX7KMT2ACAPN1 | |
| SCHEMBL30157290 | 0.83 | P2RX7 (0.53) | P2RX7KMT2ACAPN1 | |
| SCHEMBL30157849 | 0.82 | SLC6A4 (0.43) | P2RX7TSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30157362 | 0.82 | ALDH1A1 (0.59) | P2RX7TSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30157407 | 0.81 | BRD4 (0.47) | CYP2C9CYP2C19KMT2ALMNA | |
| SCHEMBL30157712 | 0.80 | KMT2A (0.57) | CYP2C9CYP2C19GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |