Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157679 | 0.91 | P2RX7 (0.39) | P2RX7HTTLMNAGAAMAPT | |
| SCHEMBL30157740 | 0.86 | P2RX7 (0.48) | P2RX7KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL30157287 | 0.86 | P2RX7 (0.48) | P2RX7KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL30158085 | 0.86 | P2RX7 (0.48) | P2RX7KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL30157806 | 0.83 | CYP3A4 (0.37) | P2RX7HTTKMT2AALDH1A1CYP2C9 | |
| SCHEMBL30157619 | 0.82 | KMT2A (0.39) | P2RX7GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL30157799 | 0.82 | HDAC1 (0.38) | P2RX7GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL30157771 | 0.79 | HDAC1 (0.37) | P2RX7HTTGAAKMT2AMEN1 | |
| SCHEMBL30157493 | 0.78 | P2RX7 (0.54) | P2RX7HTTLMNAGAAMAPT | |
| SCHEMBL30157555 | 0.77 | P2RX7 (0.52) | P2RX7HTTLMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |