Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157619 | 0.89 | KMT2A (0.39) | HDAC1HDAC2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL30157799 | 0.88 | HDAC1 (0.38) | HDAC1HDAC2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL30157806 | 0.81 | CYP3A4 (0.37) | HDAC1HDAC2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL30157508 | 0.80 | LMNA (0.40) | HDAC1HDAC2KMT2AMEN1ATM | |
| SCHEMBL30157679 | 0.80 | P2RX7 (0.39) | HDAC1HDAC2KMT2AMEN1CYP2C9 | |
| SCHEMBL30158019 | 0.80 | KMT2A (0.40) | HDAC1HDAC2KMT2AMEN1ATM | |
| SCHEMBL30157385 | 0.79 | P2RX7 (0.46) | HDAC1HDAC2KMT2AMEN1CYP2C9 | |
| SCHEMBL30158432 | 0.79 | KMT2A (0.43) | HDAC1HDAC2KMT2AMEN1ATM | |
| SCHEMBL30158085 | 0.77 | P2RX7 (0.48) | HDAC1HDAC2KMT2AMEN1P2RX7 | |
| SCHEMBL30158714 | 0.77 | KMT2A (0.56) | HDAC1HDAC2KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |