Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157451 | 0.95 | GAA (0.67) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30158807 | 0.94 | GAA (0.74) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30157665 | 0.91 | KMT2A (0.75) | POLBMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30157604 | 0.88 | GAA (0.68) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30157734 | 0.87 | GAA (0.63) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30158025 | 0.85 | NPSR1 (0.69) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30157749 | 0.85 | POLB (0.80) | POLBMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30157592 | 0.83 | GAA (0.64) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30157830 | 0.82 | P2RX7 (0.72) | POLBMEN1KMT2AGAATDP1 | |
| SCHEMBL30158012 | 0.82 | MEN1 (0.68) | POLBMEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |