Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157844 | 0.98 | TSHR (0.68) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157691 | 0.85 | ALDH1A1 (0.73) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157903 | 0.81 | ALDH1A1 (0.73) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157592 | 0.81 | GAA (0.64) | ALDH1A1LMNASMN1; SMN2NPSR1GAA | |
| SCHEMBL30157944 | 0.81 | MEN1 (0.59) | ALDH1A1SMN1; SMN2CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL30157718 | 0.81 | SMN1; SMN2 (0.93) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157765 | 0.79 | ALDH1A1 (0.98) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29354824 | 0.78 | ALDH1A1 (0.79) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157599 | 0.78 | P2RX7 (0.71) | TSHRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30157997 | 0.78 | SMN1; SMN2 (0.64) | TSHRALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |