Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157407 | 0.87 | BRD4 (0.47) | KMT2ABRD4 | |
| SCHEMBL30157408 | 0.85 | SIGMAR1 (0.51) | SIGMAR1KMT2AP2RX7ALDH1A1TSHR | |
| SCHEMBL31705306 | 0.85 | KMT2A (0.48) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL30157643 | 0.84 | SIGMAR1 (0.42) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL30157505 | 0.84 | KMT2A (0.45) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL30157854 | 0.84 | KMT2A (0.47) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL31705797 | 0.83 | KMT2A (0.48) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL30157523 | 0.83 | KMT2A (0.48) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL31706402 | 0.81 | ITGB1 (0.43) | SIGMAR1NPC1KMT2ARAB9AP2RX7 | |
| SCHEMBL31706325 | 0.81 | ALDH1A1 (0.43) | SIGMAR1NPC1KMT2ARAB9AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |