Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 11/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158726 | 1.00 | ITGA4 (0.50) | ITGA4ITGB1P2RX7CAPN1LMNA | |
| SCHEMBL30862584 | 0.88 | P2RX7 (0.47) | ITGA4ITGB1P2RX7CAPN1 | |
| SCHEMBL30158597 | 0.87 | ITGB1 (0.53) | ITGA4ITGB1CAPN1LMNAPOLB | |
| SCHEMBL30158427 | 0.87 | ITGB1 (0.53) | ITGA4ITGB1CAPN1LMNAPOLB | |
| SCHEMBL30158566 | 0.87 | ITGB1 (0.53) | ITGA4ITGB1CAPN1LMNAPOLB | |
| SCHEMBL31551284 | 0.85 | KMT2A (0.41) | ITGA4ITGB1P2RX7CAPN1 | |
| SCHEMBL31551661 | 0.85 | KMT2A (0.41) | ITGA4ITGB1P2RX7CAPN1 | |
| SCHEMBL30157689 | 0.85 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL30157776 | 0.85 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL30157967 | 0.85 | P2RX7 (0.49) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |