Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157917 | 0.89 | P2RX7 (0.48) | P2RX7MDM2TP53USP2NPC1 | |
| SCHEMBL30157832 | 0.88 | KMT2A (0.44) | P2RX7MDM2TP53PTGER4 | |
| SCHEMBL30157505 | 0.88 | KMT2A (0.45) | P2RX7NPC1CTSLPOLBPTGER4 | |
| SCHEMBL30157706 | 0.87 | P2RX7 (0.46) | P2RX7MDM2TP53USP2NPC1 | |
| SCHEMBL30157958 | 0.87 | P2RX7 (0.46) | P2RX7MDM2TP53USP2NPC1 | |
| SCHEMBL30157646 | 0.84 | PTGER3 (0.43) | P2RX7POLBPTGER4SIGMAR1 | |
| SCHEMBL30157492 | 0.84 | KMT2A (0.44) | P2RX7PTGER4 | |
| SCHEMBL30157399 | 0.84 | KMT2A (0.55) | USP2POLBPTGER4 | |
| SCHEMBL30157731 | 0.83 | KMT2A (0.42) | P2RX7PTGER4 | |
| SCHEMBL31706314 | 0.83 | P2RX7 (0.52) | P2RX7MDM2TP53USP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |