Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MTR | Q99707 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157832 | 0.90 | KMT2A (0.44) | KMT2AALDH1A1PTGER4KDM4EMAPT | |
| SCHEMBL30157399 | 0.88 | KMT2A (0.55) | KMT2AALDH1A1PTGER4KDM4EMAPT | |
| SCHEMBL30157492 | 0.88 | KMT2A (0.44) | KMT2AALDH1A1PTGER4KDM4EMAPT | |
| SCHEMBL30158819 | 0.84 | KMT2A (0.43) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL30158019 | 0.84 | KMT2A (0.40) | KMT2AALDH1A1PTGER4GAACYP2C9 | |
| SCHEMBL30158644 | 0.83 | P2RX7 (0.51) | PTGER4P2RX7 | |
| SCHEMBL30157646 | 0.82 | PTGER3 (0.43) | KMT2AALDH1A1PTGER4KDM4EGAA | |
| SCHEMBL30157641 | 0.81 | SLC6A4 (0.48) | KMT2AALDH1A1KDM4EGAACYP2C9 | |
| SCHEMBL30158003 | 0.80 | P2RX7 (0.56) | KMT2AALDH1A1MAPTGAACYP2C9 | |
| SCHEMBL30157811 | 0.80 | P2RX7 (0.42) | KMT2AALDH1A1PTGER4MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |