Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158494 | 1.00 | GFER (0.38) | GFERKDM4EALDH1A1CYP3A4RECQL | |
| SCHEMBL30158700 | 0.88 | KMT2A (0.43) | GFERKDM4EALDH1A1CYP3A4RECQL | |
| SCHEMBL30158650 | 0.85 | P2RX7 (0.37) | GFERCYP3A4KMT2AMEN1P2RX7 | |
| SCHEMBL30158630 | 0.84 | KMT2A (0.37) | KDM4EALDH1A1KMT2AITGB1ITGA4 | |
| SCHEMBL30158632 | 0.81 | ITGB1 (0.43) | KDM4EALDH1A1CYP3A4RECQLTDP1 | |
| SCHEMBL30158638 | 0.81 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL30158536 | 0.81 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL30158924 | 0.81 | ITGB1 (0.52) | ALDH1A1ITGB1ITGA4 | |
| SCHEMBL30158626 | 0.80 | ALDH1A1 (0.49) | GFERKDM4EALDH1A1CYP3A4RECQL | |
| SCHEMBL30157407 | 0.78 | BRD4 (0.47) | GFERCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |