Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NCOA2 | Q15596 | 2/20 | 1.00 |
| ▸ | NCOA1 | Q15788 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | TP53 | P04637 | 6/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015255 | 0.91 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3031698 | 0.90 | ALDH1A1 (0.83) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3031066 | 0.90 | ALDH1A1 (0.83) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3025966 | 0.84 | ALDH1A1 (0.90) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3010248 | 0.83 | ALDH1A1 (0.81) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3017289 | 0.81 | ALDH1A1 (0.81) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3026090 | 0.81 | MAPT (0.81) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3010549 | 0.80 | ALDH1A1 (0.81) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3022076 | 0.80 | ALDH1A1 (0.81) | MAPTALDH1A1MEN1PPARGKMT2A | |
| SCHEMBL3017234 | 0.80 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | claimed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | claimed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | claimed |
| US-9316633-B2 | Methods for identifying inhibitors of solute transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-04-19 | — | — | US | disclosed |
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | SLC2A1, SLC2A3, SLC2A8 | MAPT 1849/4885ALDH1A1 3404/4885MEN1 1626/4885 |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | SLC14A1, SLCO4C1, SLCO2B1 | MAPT 584/4885ALDH1A1 2350/4885MEN1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.