Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858360 | 0.75 | ALDH1A1 (0.62) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6243579 | 0.75 | ALDH1A1 (0.62) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6971456 | 0.75 | LMNA (0.48) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6982576 | 0.72 | CHRM2 (0.58) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3960105 | 0.71 | ALDH1A1 (0.53) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22692293 | 0.70 | CA12 (0.46) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL791221 | 0.70 | ALDH1A1 (0.75) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7008960 | 0.70 | ALDH1A1 (0.52) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13476544 | 0.69 | ALDH1A1 (0.54) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13801259 | 0.68 | SMN1; SMN2 (0.50) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535598-B2 | Histone deacetylases (HDACs) inhibitors | Annji Pharmaceutical Co., Ltd. (TW) | 2022-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535598-B2 | Histone deacetylases (HDACs) inhibitors | HDAC1, HDAC3, HDAC2 | ALDH1A1 485/4885ADORA3 4570/4885ADORA2A 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.