Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261013 | 1.00 | NPSR1 (0.53) | NPSR1FFAR1FFAR4KEAP1 | |
| SCHEMBL14110345 | 0.89 | NPSR1 (0.53) | NPSR1FFAR1FFAR4KEAP1 | |
| SCHEMBL15355980 | 0.85 | FFAR1 (0.52) | FFAR1FFAR4KEAP1 | |
| SCHEMBL14369972 | 0.83 | NPSR1 (0.47) | NPSR1FFAR1FFAR4 | |
| SCHEMBL585013 | 0.83 | FFAR4 (0.58) | NPSR1FFAR1FFAR4KEAP1 | |
| SCHEMBL18541177 | 0.82 | PKM (0.51) | FFAR1FFAR4KEAP1 | |
| SCHEMBL29901118 | 0.81 | CYP4F2 (0.45) | — | |
| SCHEMBL1750638 | 0.81 | FFAR1 (0.51) | FFAR1FFAR4KEAP1 | |
| SCHEMBL12451965 | 0.80 | PPARA (0.56) | FFAR1FFAR4 | |
| SCHEMBL20289308 | 0.80 | CYP4F2 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |