SCHEMBL585013

SCHEMBL585013

Cc1ccc(CCC(=O)O)cc1C

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 8/20 0.58
FFAR1 O14842 12/20 0.56
NPSR1 Q6W5P4 1/20 0.53
KEAP1 Q14145 1/20 0.52
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453481 0.89 CYP1A2 (0.57) FFAR4FFAR1NPSR1ALDH1A1
SCHEMBL28106880 0.86 IAPP (0.53) FFAR4FFAR1
SCHEMBL11218783 0.85 THRA (0.57) FFAR4FFAR1NPSR1KEAP1
SCHEMBL18161715 0.85 FFAR1 (0.53) FFAR4FFAR1NPSR1KEAP1
SCHEMBL4632516 0.84 ALDH1A1 (0.53) FFAR4FFAR1ALDH1A1
Phenyl Propionic Acid SCHEMBL28555657 0.83 FFAR4 (0.58) FFAR4FFAR1KEAP1
SCHEMBL24893771 0.83 FFAR1 (0.59) FFAR4FFAR1NPSR1KEAP1
SCHEMBL16899346 0.83 FFAR4 (0.54) FFAR4FFAR1NPSR1KEAP1
SCHEMBL14110345 0.83 NPSR1 (0.53) FFAR4FFAR1NPSR1KEAP1
SCHEMBL14430305 0.83 FFAR4 (0.54) FFAR4FFAR1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2022-02-22 US disclosed
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS NOVO NORDISK A/S (DK) 2020-12-31 US disclosed
US-10456472-B2 Phenylalkylcarboxylic acid delivery agents EMISPHERE TECHNOLOGIES, INC. (US) 2019-10-29 US disclosed
US-9938204-B2 Intermolecular C-H silylation of unactivated arenes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-04-10 US disclosed
EP-2114145-B1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECH INC (US) 2017-11-01 EP disclosed
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US disclosed
US-20160375135-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2016-12-29 US disclosed
US-20160200639-A1 INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-07-14 US disclosed
US-9365504-B2 Salts of kukoamine B, preparation method and use thereof THE FIRST AFFILIATED HOSPITAL, THIRD MILITARY UNIVERSITY, PLA (CN) 2016-06-14 US disclosed
US-20130289112-A1 SALTS OF KUKOAMINE B, PREPARATION METHOD AND USE THEREOF TIANJIN CHASESUN PHARMACEUTICAL CO., LTD (CN) 2013-10-31 US disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed
EP-0721939-B1 N-arylalkylphenylacetamide derivatives KOREA RES INST CHEM TECH (KR) 1998-04-15 EP disclosed
EP-0525360-B1 Novel phenylacetamide derivatives and processes for the preparation thereof KOREA RES INST CHEM TECH (KR) 1998-03-25 EP disclosed
US-5670546-A ANALGESICS, ANTIINFLAMMATORY AGENTS, RELATED TO CAPSAICIN BUT WITHOUT UNDESIRABLE SIDE EFFECTS KOREAN RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-09-23 US disclosed
EP-0721939-A1 N-arylalkylphenylacetamide derivatives Korea Research Institute of Chemical Technology (KR) 1996-07-17 EP disclosed
US-5242944-A Analgesics or antiinflammatory agents KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-09-07 US disclosed
EP-0525360-A2 Novel phenylacetamide derivatives and processes for the preparation thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-02-03 EP disclosed
US-4026896-A ANTIALLERGENS KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200639-A1 INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES CCNH, CTTN, CCRL2 FFAR4 2766/4885FFAR1 3159/4885NPSR1 2527/4885
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA FFAR4 697/4885FFAR1 713/4885NPSR1 1464/4885
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 FFAR4 3270/4885FFAR1 2377/4885NPSR1 1766/4885
US-10456472-B2 Phenylalkylcarboxylic acid delivery agents PGF, LIPA, PDGFA FFAR4 697/4885FFAR1 713/4885NPSR1 1464/4885
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents PGF, LIPA, PDGFA FFAR4 697/4885FFAR1 713/4885NPSR1 1464/4885
US-20130289112-A1 SALTS OF KUKOAMINE B, PREPARATION METHOD AND USE THEREOF TLR4, BDKRB1, KLKB1 FFAR4 2542/4885FFAR1 2461/4885NPSR1 1008/4885
US-20160375135-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA FFAR4 697/4885FFAR1 713/4885NPSR1 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.