Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 5/20 | 0.52 |
| ▸ | NCF1 | P14598 | 8/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159453 | 0.79 | PRMT5 (0.49) | METTL3PRMT5WDR77 | |
| SCHEMBL30159566 | 0.75 | METTL3 (0.50) | METTL3PRMT5WDR77 | |
| SCHEMBL30159329 | 0.74 | PRMT5 (0.51) | METTL3NCF1PRMT5 | |
| SCHEMBL23452962 | 0.72 | NCF1 (0.90) | NCF1 | |
| SCHEMBL23452966 | 0.70 | NCF1 (0.74) | NCF1 | |
| SCHEMBL23412662 | 0.68 | NCF1 (1.00) | NCF1 | |
| SCHEMBL23412247 | 0.68 | NCF1 (1.00) | NCF1 | |
| SCHEMBL23412696 | 0.68 | NCF1 (1.00) | NCF1 | |
| SCHEMBL23413036 | 0.68 | NCF1 (1.00) | NCF1 | |
| SCHEMBL23412164 | 0.68 | NCF1 (1.00) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001133-A1 | PRMT5 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2023-01-26 | — | — | WO | disclosed |