Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849951 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL25078626 | 0.85 | HSD17B10 (0.44) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL2459873 | 0.84 | KMT2A (0.52) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL16503320 | 0.80 | CA1 (0.58) | ALDH1A1HSD17B10KDM4ELMNAP2RX3 | |
| SCHEMBL22229984 | 0.78 | HSD17B10 (0.42) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL16503321 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4ELMNAP2RX3 | |
| SCHEMBL142307 | 0.78 | KDM4E (0.53) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL1504529 | 0.77 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL25078533 | 0.76 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4ELMNAHTT | |
| SCHEMBL30949243 | 0.76 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | ABL2, ABL1, ALK | ALDH1A1 651/4885L3MBTL1 2917/4885HSD17B10 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.