SCHEMBL30159533 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	PKN1	Q16512	1/20	0.41

▸	PKN2	Q16513	1/20	0.41

▸	F10	P00742	7/20	0.38

▸	PTGER4	P35408	2/20	0.38

▸	PARP1	P09874	2/20	0.38

▸	CA9	Q16790	4/20	0.37

▸	CA2	P00918	2/20	0.37

▸	CA1	P00915	1/20	0.37

▸	CA5A	P35218	1/20	0.37

▸	CA12	O43570	2/20	0.35

▸	P2RX3	P56373	1/20	0.35

▸	IDH1	O75874	1/20	0.35

▸	NNMT	P40261	1/20	0.34

▸	HSD11B1	P28845	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23529352	0.85	PKN1 (0.45)	PKN1PKN2PTGER4PARP1
SCHEMBL23552540	0.84	PKN1 (0.47)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL29948181	0.84	PKN1 (0.47)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL29948122	0.81	PKN1 (0.42)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL23552630	0.81	PKN1 (0.42)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL23552535	0.80	PKN1 (0.43)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL29948149	0.80	PKN1 (0.43)	PKN1PKN2PTGER4PARP1IDH1
SCHEMBL30042716	0.79	PKN1 (0.45)	PKN1PKN2PTGER4PARP1
SCHEMBL23529311	0.79	AGTR1 (0.42)	—
SCHEMBL24801176	0.78	PKN1 (0.41)	PKN1PKN2PTGER4PARP1IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022266711-A1	SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS	Aculeus Therapeutics Pty Ltd (AU)	2022-12-29	—	—	WO	disclosed