SCHEMBL30160465

SCHEMBL30160465

C=CC(=O)N(C)Cc1oc2ccc(O)cc2c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 2/20 0.42
EYA3 Q99504 2/20 0.42
MAPT P10636 4/20 0.39
POLB P06746 2/20 0.39
GAA P10253 2/20 0.39
MMP14 P50281 1/20 0.39
RAB9A P51151 1/20 0.39
MAPK1 P28482 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
PKM P14618 1/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23532095 1.00 SLC22A12 (0.42) SLC22A12EYA3MAPTPOLBGAA
SCHEMBL15999473 0.89 PKM (0.48) RAB9AALDH1A1PKMMEN1KMT2A
SCHEMBL725375 0.83 HCRTR1 (0.41) RAB9APKMKMT2ACYP2C19HTT
Hydrochloric Acid SCHEMBL4794398 0.82 HCRTR1 (0.41) RAB9APKMKMT2ACYP2C19HTT
SCHEMBL15999427 0.81 PKM (0.38) MAPTPOLBRAB9AKDM4EPKM
Trifluoroacetic Acid SCHEMBL4777187 0.76 HCRTR1 (0.39) RAB9APKMKMT2AHTTSMN1; SMN2
SCHEMBL23532149 0.76 CSF1R (0.40) RAB9ALMNATDP1
SCHEMBL23532028 0.76 ALOX5 (0.44) MAPTRAB9A
Hydrochloric Acid SCHEMBL29958794 0.75 CSF1R (0.39) RAB9ALMNATDP1
SCHEMBL27238873 0.75 HCRTR1 (0.40) RAB9AMEN1KMT2ACYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077324-A1 NOVEL COMPOUNDS AND THEIR USE Debiopharm International SA (CH) 2022-10-26 EP disclosed