Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20499954 | 1.00 | OPRM1 (0.49) | OPRM1OPRK1 | |
| SCHEMBL20670698 | 0.89 | OPRK1 (0.51) | OPRM1OPRK1 | |
| SCHEMBL20670475 | 0.84 | OPRM1 (0.58) | OPRM1OPRK1 | |
| SCHEMBL20670583 | 0.83 | OPRM1 (0.50) | OPRM1OPRK1 | |
| SCHEMBL20500041 | 0.82 | OPRK1 (0.53) | OPRM1OPRK1 | |
| SCHEMBL20499978 | 0.82 | OPRK1 (0.45) | OPRM1OPRK1 | |
| SCHEMBL20499945 | 0.81 | OPRK1 (0.53) | OPRM1OPRK1 | |
| SCHEMBL20670579 | 0.81 | OPRK1 (0.46) | OPRM1OPRK1 | |
| SCHEMBL29664055 | 0.81 | OPRK1 (0.46) | OPRM1OPRK1 | |
| SCHEMBL24611001 | 0.79 | OPRK1 (0.42) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4141001-A1 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | The Scripps Research Institute (US) | 2023-03-01 | — | — | EP | disclosed |