Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854764 | 0.75 | HRH4 (0.39) | HRH4SCD | |
| SCHEMBL27917197 | 0.72 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28801191 | 0.71 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL3328268 | 0.70 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL16432263 | 0.70 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL23556133 | 0.70 | CRBN (0.43) | HRH4 | |
| SCHEMBL13787617 | 0.68 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL22042060 | 0.67 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL16404868 | 0.67 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBALDH1A1SMN1; SMN2 | |
| SCHEMBL4120139 | 0.67 | ABCC2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002408-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002408-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | HAVCR2, HCCS, PYGL | PIK3CD 1786/4885PIK3CA 1701/4885PIK3CB 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.