Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 16/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.42 |
| ▸ | CCND1 | P24385 | 10/20 | 0.42 |
| ▸ | CCND2 | P30279 | 6/20 | 0.42 |
| ▸ | CCND3 | P30281 | 6/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851900 | 1.00 | CDK4 (0.44) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL24851095 | 0.99 | CDK4 (0.43) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL30161877 | 0.99 | CDK4 (0.43) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL24851156 | 0.92 | CDK4 (0.43) | CDK4CDK6CCND1CDK2CASP1 | |
| SCHEMBL30162222 | 0.89 | CASP1 (0.49) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL24851468 | 0.89 | CASP1 (0.49) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL30161870 | 0.85 | CASP1 (0.37) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL24851195 | 0.85 | CASP1 (0.37) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL24851179 | 0.84 | CDK4 (0.49) | CDK4CDK6CCND1CCND2CCND3 | |
| SCHEMBL30162044 | 0.84 | CDK4 (0.49) | CDK4CDK6CCND1CCND2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |