Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163546 | 0.91 | MAPT (0.41) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428617 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428538 | 0.86 | HPGD (0.46) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30163475 | 0.86 | L3MBTL3 (0.42) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428440 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31428503 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30163525 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428674 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428623 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428528 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |