Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976072 | 0.91 | AKT1 (0.38) | MAPK1SMN1; SMN2ALDH1A1MAPTAKT1 | |
| SCHEMBL30163525 | 0.89 | ALDH1A1 (0.38) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL31428617 | 0.87 | ALDH1A1 (0.45) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL30163521 | 0.86 | ALDH1A1 (0.45) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL31428538 | 0.86 | HPGD (0.46) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL31428440 | 0.85 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31428503 | 0.85 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL31428867 | 0.84 | PKM (0.44) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL30163546 | 0.84 | MAPT (0.41) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL31428674 | 0.83 | ALDH1A1 (0.40) | MAPK1SMN1; SMN2TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | MAPK1 140/4885SMN1; SMN2 4832/4885TDP1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.