Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301476 | 0.91 | ALDH1A1 (0.47) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301621 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301759 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301831 | 0.85 | ALDH1A1 (0.47) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301624 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301438 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL10005231 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL21477194 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL21477058 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL302583 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1USP2ALOX15GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404924-B1 | Aqueous solution of piperazinyl-containing silanol compound and making method | SHINETSU CHEMICAL CO (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-20120006229-A1 | AQUEOUS SOLUTION OF PIPERAZINYL-CONTAINING SILANOL COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| EP-2404924-A1 | Aqueous solution of piperazinyl-containing silanol compound and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |