Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211186 | 1.00 | KMT2A (0.64) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL5806478 | 0.89 | KMT2A (0.67) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL5806483 | 0.89 | KMT2A (0.67) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL21048453 | 0.81 | KMT2A (0.68) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL16829044 | 0.81 | KMT2A (0.68) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL13319545 | 0.76 | ALDH1A1 (0.62) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL19502792 | 0.75 | KMT2A (0.60) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL19502791 | 0.75 | KMT2A (0.60) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29485531 | 0.74 | ATM (0.61) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL17298921 | 0.72 | KMT2A (0.57) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
| EP-1979332-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007083089-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197749-A1 | CHEMICAL COMPOUNDS | EDF1, ECE1, EDNRA | KMT2A 2713/4885TSHR 4410/4885HSD17B10 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.